AMS Laboratories - Antibiotic Potency Tests


	Company Information Sterility Testing Disinfectant Mycoplasma Testing Antibiotic Potency Assays Preservative Efficacy Testing AS NZS 4020 Tests AMES Testing Credentials Submit Samples Terms of Trade Downloads Useful Links ContactInformation News April 2008 September 2008 November 2008 December 2008 March 2009 April 2010



Antibiotic Potency Tests


BACKGROUND: AMS Laboratories are able to perform antibiotic potency testing by the bioassay method. Antibiotic potency is estimated by comparing the inhibition of growth of sensitive micro-organisms produced by known concentrations of the antibiotic being examined against a reference standard substance. The test is performed on raw materials and finished products to confirm the antibiotic activity meets specifications. PRINCIPLE OF TEST: All test methods are based on the European and British Pharmacopeia: Biological assay of antibiotics, BP Appendix XIV A (Ph. Eur. method 2.7.2) This is a large-plate format procedure where test and standard preparations are loaded into wells in a randomized latin square arrangement before incubation and reading the zones of inhibition. List of methods/antimicrobials available: Amphotericin B Bacitracin Bleomycin Colistin Colistimethate Dihydrostreptomycin Erythromycin Framycetin Gentamicin Kanamycin Neomycin Netilmicin Nystatin Polymyxin B Rifamycin Spiramycin Streptomycin Tobramycin Tylosin Vancomycin We can also perform Antimicrobial Activity Tests such as the Minimum Inhibition Concentration (MIC) Test Minimum Bactericidal Concentration (MBC) Test Minimum Kill Concentration ( MKC) Test Zone of Inhibition (ZOI) Test SAMPLE REQUIREMENTS and TURNAROUND TIMES: AS these will vary with the type of product and study required, please contact the laboratory to discuss your needs.